New real-time-PCR method to identify single point mutations in hepatitis C virus

AIM: To develop a fast, low-cost diagnostic strategy to identify single point mutations in highly variable genomes such as hepatitis C virus (HCV). METHODS: In patients with HCV infection, resistance-associated amino acid substitutions within the viral quasispecies prior to therapy can confer decrea...

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Dettagli Bibliografici
Pubblicato in:World J Gastroenterol
Autori principali: Chen, Qian, Belmonte, Irene, Buti, Maria, Nieto, Leonardo, Garcia-Cehic, Damir, Gregori, Josep, Perales, Celia, Ordeig, Laura, Llorens, Meritxell, Soria, Maria Eugenia, Esteban, Rafael, Esteban, Juan Ignacio, Rodriguez-Frias, Francisco, Quer, Josep
Natura: Artigo
Lingua:Inglês
Pubblicazione: Baishideng Publishing Group Inc 2016
Soggetti:
Observational Study
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116604/
https://ncbi.nlm.nih.gov/pubmed/27920481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v22.i43.9604
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