Ultra-Deep Pyrosequencing (UDPS) Data Treatment to Study Amplicon HCV Minor Variants

We have investigated the reliability and reproducibility of HCV viral quasispecies quantification by ultra-deep pyrosequencing (UDPS) methods. Our study has been divided in two parts. First of all, by UDPS sequencing of clone mixes samples we have established the global noise level of UDPS and fine...

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Autors principals: Gregori, Josep, Esteban, Juan I., Cubero, María, Garcia-Cehic, Damir, Perales, Celia, Casillas, Rosario, Alvarez-Tejado, Miguel, Rodríguez-Frías, Francisco, Guardia, Jaume, Domingo, Esteban, Quer, Josep
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877031/
https://ncbi.nlm.nih.gov/pubmed/24391758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083361
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