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Transcription factor IRF8 orchestrates the adaptive natural killer cell response

Natural killer (NK) cells are innate lymphocytes that display features of adaptive immunity during viral infection. Biallelic mutations in IRF8 have been reported to cause familial NK cell deficiency and susceptibility to severe viral infection in humans; however, the precise role of this transcript...

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Bibliografische gegevens
Gepubliceerd in:Immunity
Hoofdauteurs: Adams, Nicholas M., Lau, Colleen M., Fan, Xiying, Rapp, Moritz, Geary, Clair D., Weizman, Orr-El, Diaz-Salazar, Carlos, Sun, Joseph C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233715/
https://ncbi.nlm.nih.gov/pubmed/29858012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.04.018
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