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Transcription factor IRF8 orchestrates the adaptive natural killer cell response

Natural killer (NK) cells are innate lymphocytes that display features of adaptive immunity during viral infection. Biallelic mutations in IRF8 have been reported to cause familial NK cell deficiency and susceptibility to severe viral infection in humans; however, the precise role of this transcript...

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Bibliografski detalji
Izdano u:Immunity
Glavni autori: Adams, Nicholas M., Lau, Colleen M., Fan, Xiying, Rapp, Moritz, Geary, Clair D., Weizman, Orr-El, Diaz-Salazar, Carlos, Sun, Joseph C.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233715/
https://ncbi.nlm.nih.gov/pubmed/29858012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.04.018
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