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IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development
B-lymphocyte development involves sequential DNA rearrangements of immunoglobulin (Ig) heavy (μ) and light (κ, λ) chain loci and is dependent on transient expression of μ containing pre-antigen receptor complexes (pre-BCR). To date, genetic analysis has not identified transcription factors that coor...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC196178/ https://ncbi.nlm.nih.gov/pubmed/12832394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1104803 |
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