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IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development

B-lymphocyte development involves sequential DNA rearrangements of immunoglobulin (Ig) heavy (μ) and light (κ, λ) chain loci and is dependent on transient expression of μ containing pre-antigen receptor complexes (pre-BCR). To date, genetic analysis has not identified transcription factors that coor...

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Detalhes bibliográficos
Main Authors: Lu, Runqing, Medina, Kay L., Lancki, David W., Singh, Harinder
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC196178/
https://ncbi.nlm.nih.gov/pubmed/12832394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1104803
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