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Transcription factor IRF8 orchestrates the adaptive natural killer cell response

Natural killer (NK) cells are innate lymphocytes that display features of adaptive immunity during viral infection. Biallelic mutations in IRF8 have been reported to cause familial NK cell deficiency and susceptibility to severe viral infection in humans; however, the precise role of this transcript...

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Bibliografiske detaljer
Udgivet i:Immunity
Main Authors: Adams, Nicholas M., Lau, Colleen M., Fan, Xiying, Rapp, Moritz, Geary, Clair D., Weizman, Orr-El, Diaz-Salazar, Carlos, Sun, Joseph C.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233715/
https://ncbi.nlm.nih.gov/pubmed/29858012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.04.018
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