Cholesterol-dependent cytolysins: from water-soluble state to membrane pore

The cholesterol-dependent cytolysins (CDCs) are a family of bacterial toxins that are important virulence factors for a number of pathogenic Gram-positive bacterial species. CDCs are secreted as soluble, stable monomeric proteins that bind specifically to cholesterol-rich cell membranes, where they...

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Bibliografiske detaljer
Udgivet i:Biophys Rev
Main Authors: Christie, Michelle P., Johnstone, Bronte A., Tweten, Rodney K., Parker, Michael W., Morton, Craig J.
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2018
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233344/
https://ncbi.nlm.nih.gov/pubmed/30117093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-018-0448-x
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