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TOR complex 2–regulated protein kinase Ypk1 controls sterol distribution by inhibiting StARkin domain–containing proteins located at plasma membrane–endoplasmic reticulum contact sites

In our proteome-wide screen, Ysp2 (also known as Lam2/Ltc4) was identified as a likely physiologically relevant target of the TOR complex 2 (TORC2)–dependent protein kinase Ypk1 in the yeast Saccharomyces cerevisiae. Ysp2 was subsequently shown to be one of a new family of sterol-binding proteins lo...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Roelants, Françoise M., Chauhan, Neha, Muir, Alexander, Davis, Jameson C., Menon, Anant K., Levine, Timothy P., Thorner, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232965/
https://ncbi.nlm.nih.gov/pubmed/29927351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-04-0229
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