TORC2-Dependent Ypk1-Mediated Phosphorylation of Lam2/Ltc4 Disrupts Its Association with the β-Propeller Protein Laf1 at Endoplasmic Reticulum-Plasma Membrane Contact Sites in the Yeast Saccharomyces cerevisiae

Membrane-tethered sterol-binding Lam/Ltc proteins localize at junctions between the endoplasmic reticulum (ER) membrane and other organelles. Two of the six family members—Lam2/Ltc4 (initially Ysp2) and paralog Lam4/Ltc3—localize to ER-plasma membrane (PM) contact sites (CSs) and mediate retrograde...

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Publié dans:Biomolecules
Auteurs principaux: Topolska, Magdalena, Roelants, Françoise M., Si, Edward P., Thorner, Jeremy
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760575/
https://ncbi.nlm.nih.gov/pubmed/33255682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10121598
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