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TORC2-dependent protein kinase Ypk1 phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids

Plasma membrane lipid composition must be maintained during growth and under environmental insult. In yeast, signaling mediated by TOR Complex 2 (TORC2)-dependent protein kinase Ypk1 controls lipid abundance and distribution in response to membrane stress. Ypk1, among other actions, alleviates negat...

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Bibliografiske detaljer
Main Authors: Muir, Alexander, Ramachandran, Subramaniam, Roelants, Françoise M, Timmons, Garrett, Thorner, Jeremy
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217029/
https://ncbi.nlm.nih.gov/pubmed/25279700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03779
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