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Exchange of water for sterol underlies sterol egress from a StARkin domain
Previously we identified Lam/GramD1 proteins, a family of endoplasmic reticulum membrane proteins with sterol-binding StARkin domains that are implicated in intracellular sterol homeostasis. Here, we show how these proteins exchange sterol molecules with membranes. An aperture at one end of the StAR...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6940019/ https://ncbi.nlm.nih.gov/pubmed/31799930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53444 |
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