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A Novel Chimeric Oncolytic Virus Vector for Improved Safety and Efficacy as a Platform for the Treatment of Hepatocellular Carcinoma

Oncolytic viruses represent an exciting new aspect of the evolving field of cancer immunotherapy. We have engineered a novel hybrid vector comprising vesicular stomatitis virus (VSV) and Newcastle disease virus (NDV), named recombinant VSV-NDV (rVSV-NDV), wherein the VSV backbone is conserved but it...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Abdullahi, Sarah, Jäkel, Melanie, Behrend, Sabine J., Steiger, Katja, Topping, Geoffrey, Krabbe, Teresa, Colombo, Alessio, Sandig, Volker, Schiergens, Tobias S., Thasler, Wolfgang E., Werner, Jens, Lichtenthaler, Stefan F., Schmid, Roland M., Ebert, Oliver, Altomonte, Jennifer
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232488/
https://ncbi.nlm.nih.gov/pubmed/30232179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01386-18
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