A Novel Chimeric Oncolytic Virus Vector for Improved Safety and Efficacy as a Platform for the Treatment of Hepatocellular Carcinoma

Oncolytic viruses represent an exciting new aspect of the evolving field of cancer immunotherapy. We have engineered a novel hybrid vector comprising vesicular stomatitis virus (VSV) and Newcastle disease virus (NDV), named recombinant VSV-NDV (rVSV-NDV), wherein the VSV backbone is conserved but it...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Abdullahi, Sarah, Jäkel, Melanie, Behrend, Sabine J., Steiger, Katja, Topping, Geoffrey, Krabbe, Teresa, Colombo, Alessio, Sandig, Volker, Schiergens, Tobias S., Thasler, Wolfgang E., Werner, Jens, Lichtenthaler, Stefan F., Schmid, Roland M., Ebert, Oliver, Altomonte, Jennifer
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2018
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232488/
https://ncbi.nlm.nih.gov/pubmed/30232179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01386-18
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