A Novel Chimeric Oncolytic Virus Vector for Improved Safety and Efficacy as a Platform for the Treatment of Hepatocellular Carcinoma

Oncolytic viruses represent an exciting new aspect of the evolving field of cancer immunotherapy. We have engineered a novel hybrid vector comprising vesicular stomatitis virus (VSV) and Newcastle disease virus (NDV), named recombinant VSV-NDV (rVSV-NDV), wherein the VSV backbone is conserved but it...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Abdullahi, Sarah, Jäkel, Melanie, Behrend, Sabine J., Steiger, Katja, Topping, Geoffrey, Krabbe, Teresa, Colombo, Alessio, Sandig, Volker, Schiergens, Tobias S., Thasler, Wolfgang E., Werner, Jens, Lichtenthaler, Stefan F., Schmid, Roland M., Ebert, Oliver, Altomonte, Jennifer
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232488/
https://ncbi.nlm.nih.gov/pubmed/30232179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01386-18
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