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Enhanced Safety and Efficacy of Oncolytic VSV Therapy by Combination with T Cell Receptor Transgenic T Cells as Carriers

Vesicular stomatitis virus (VSV) represents an attractive oncolytic virotherapy platform because of its potent tumor cell-killing and immune-stimulating properties; yet the clinical translation of VSV faces numerous challenges, such as inefficient systemic delivery and severe side effects such as ne...

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Опубликовано в: :Mol Ther Oncolytics
Главные авторы: Melzer, Michael Karl, Zeitlinger, Lisa, Mall, Sabine, Steiger, Katja, Schmid, Roland M., Ebert, Oliver, Krackhardt, Angela, Altomonte, Jennifer
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Gene & Cell Therapy 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325079/
https://ncbi.nlm.nih.gov/pubmed/30662938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2018.12.001
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