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Exponential Enhancement of Oncolytic VSV Potency by Vector-Mediated Suppression of Inflammatory Responses In Vivo

Oncolytic virotherapy is a promising strategy for treatment of malignancy, although its effectiveness is hampered by host anti-viral inflammatory responses. Indeed the treatment efficacy of oncolytic Vesicular Stomatitis Virus (VSV) in rats bearing multi-focal Hepatocellular Carcinoma (HCC) can be s...

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Detalhes bibliográficos
Main Authors: Altomonte, Jennifer, Wu, Lan, Chen, Li, Meseck, Marcia, Ebert, Oliver, García-Sastre, Adolfo, Fallon, John, Woo, Savio L.C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930752/
https://ncbi.nlm.nih.gov/pubmed/18071337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.mt.6300343
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