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rVSV(MΔ51)-M3 Is an Effective and Safe Oncolytic Virus for Cancer Therapy
Oncolytic vesicular stomatitis virus (VSV) is being developed as a novel therapeutic agent for cancer treatment, although it is toxic in animals when administered systemically at high doses. Its safety can be substantively improved by an MΔ51 deletion in the viral genome, and yet VSV(MΔ51) induces a...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2775926/ https://ncbi.nlm.nih.gov/pubmed/18533893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2007.163 |
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