rVSV(MΔ51)-M3 Is an Effective and Safe Oncolytic Virus for Cancer Therapy

Oncolytic vesicular stomatitis virus (VSV) is being developed as a novel therapeutic agent for cancer treatment, although it is toxic in animals when administered systemically at high doses. Its safety can be substantively improved by an MΔ51 deletion in the viral genome, and yet VSV(MΔ51) induces a...

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Dettagli Bibliografici
Autori principali: Wu, Lan, Huang, Tian-gui, Meseck, Marcia, Altomonte, Jennifer, Ebert, Oliver, Shinozaki, Katsunori, García-Sastre, Adolfo, Fallon, John, Mandeli, John, Woo, Savio L.C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2008
Soggetti:
Scientific Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775926/
https://ncbi.nlm.nih.gov/pubmed/18533893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2007.163
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