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Antifibrotic Properties of Transarterial Oncolytic VSV Therapy for Hepatocellular Carcinoma in Rats With Thioacetamide-Induced Liver Fibrosis

Recombinant vesicular stomatitis virus (VSV) shows promise for the treatment of hepatocellular carcinoma (HCC), but its safety and efficacy when administered in a setting of hepatic fibrosis, which occurs in the majority of clinical cases, is unknown. We hypothesized that VSV could provide a novel b...

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Autori principali: Altomonte, Jennifer, Marozin, Sabrina, De Toni, Enrico N, Rizzani, Antonia, Esposito, Irene, Steiger, Katja, Feuchtinger, Annette, Hellerbrand, Claus, Schmid, Roland M, Ebert, Oliver
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831039/
https://ncbi.nlm.nih.gov/pubmed/23939023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.181
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