Susceptibility to Neutralization by Broadly Neutralizing Antibodies Generally Correlates with Infected Cell Binding for a Panel of Clade B HIV Reactivated from Latent Reservoirs

Efforts to cure human immunodeficiency virus (HIV) infection are obstructed by reservoirs of latently infected CD4(+) T cells that can reestablish viremia. HIV-specific broadly neutralizing antibodies (bNAbs), defined by unusually wide neutralization breadths against globally diverse viruses, may co...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Ren, Yanqin, Korom, Maria, Truong, Ronald, Chan, Dora, Huang, Szu-Han, Kovacs, Colin C., Benko, Erika, Safrit, Jeffrey T., Lee, John, Garbán, Hermes, Apps, Richard, Goldstein, Harris, Lynch, Rebecca M., Jones, R. Brad
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2018
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232479/
https://ncbi.nlm.nih.gov/pubmed/30209173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00895-18
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