Predicting the broadly neutralizing antibody susceptibility of the HIV reservoir

Broadly neutralizing antibodies (bNAbs) against HIV-1 are under evaluation for both prevention and therapy. HIV-1 sequence diversity observed in most HIV-infected individuals and archived variations in critical bNAb epitopes present a major challenge for the clinical application of bNAbs, as preexis...

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Dettagli Bibliografici
Pubblicato in:JCI Insight
Autori principali: Yu, Wen-Han, Su, David, Torabi, Julia, Fennessey, Christine M., Shiakolas, Andrea, Lynch, Rebecca, Chun, Tae-Wook, Doria-Rose, Nicole, Alter, Galit, Seaman, Michael S., Keele, Brandon F., Lauffenburger, Douglas A., Julg, Boris
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2019
Soggetti:
Technical Advance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777915/
https://ncbi.nlm.nih.gov/pubmed/31484826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130153
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