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Establishment of a Novel Humanized Mouse Model To Investigate In Vivo Activation and Depletion of Patient-Derived HIV Latent Reservoirs
Curing HIV infection has been thwarted by the persistent reservoir of latently infected CD4(+) T cells, which reinitiate systemic infection after antiretroviral therapy (ART) interruption. To evaluate reservoir depletion strategies, we developed a novel preclinical in vivo model consisting of immuno...
Guardat en:
| Publicat a: | J Virol |
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| Autors principals: | , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6401459/ https://ncbi.nlm.nih.gov/pubmed/30626677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02051-18 |
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