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The Intact Noninducible Latent HIV-1 Reservoir Is Established in an In Vitro Primary T(CM) Cell Model of Latency

The establishment of HIV-1 latency has hindered an HIV-1 cure. “Shock and kill” strategies to target this reservoir aim to induce the latent provirus with latency-reversing agents (LRAs). However, recent studies have shown that the majority of the intact HIV-1 viral reservoir found in antiretroviral...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Sarabia, Indra, Huang, Szu-Han, Ward, Adam R., Jones, R. Brad, Bosque, Alberto
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092701/
https://ncbi.nlm.nih.gov/pubmed/33441346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01297-20
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