Latent HIV reservoirs exhibit inherent resistance to elimination by CD8(+) T cells

The presence of persistent, latent HIV reservoirs in CD4(+) T cells obstructs current efforts to cure infection. The so-called kick-and-kill paradigm proposes to purge these reservoirs by combining latency-reversing agents with immune effectors such as cytotoxic T lymphocytes. Support for this appro...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Clin Invest
Egile Nagusiak: Huang, Szu-Han, Ren, Yanqin, Thomas, Allison S., Chan, Dora, Mueller, Stefanie, Ward, Adam R., Patel, Shabnum, Bollard, Catherine M., Cruz, Conrad Russell, Karandish, Sara, Truong, Ronald, Macedo, Amanda B., Bosque, Alberto, Kovacs, Colin, Benko, Erika, Piechocka-Trocha, Alicja, Wong, Hing, Jeng, Emily, Nixon, Douglas F., Ho, Ya-Chi, Siliciano, Robert F., Walker, Bruce D., Jones, R. Brad
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2018
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785246/
https://ncbi.nlm.nih.gov/pubmed/29355843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI97555
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