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Latent HIV reservoirs exhibit inherent resistance to elimination by CD8(+) T cells
The presence of persistent, latent HIV reservoirs in CD4(+) T cells obstructs current efforts to cure infection. The so-called kick-and-kill paradigm proposes to purge these reservoirs by combining latency-reversing agents with immune effectors such as cytotoxic T lymphocytes. Support for this appro...
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| Publicado no: | J Clin Invest |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5785246/ https://ncbi.nlm.nih.gov/pubmed/29355843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI97555 |
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