Reovirus Neurotropism and Virulence Are Dictated by Sequences in the Head Domain of the Viral Attachment Protein

Viral capsid components that bind cellular receptors mediate critical functions in viral tropism and disease pathogenesis. Mammalian orthoreoviruses (reoviruses) spread systemically in newborn mice to cause serotype-specific disease in the central nervous system (CNS). Serotype 1 (T1) reovirus infec...

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Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Sutherland, Danica M., Aravamudhan, Pavithra, Dietrich, Melanie H., Stehle, Thilo, Dermody, Terence S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2018
Konular:
Pathogenesis and Immunity
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232475/
https://ncbi.nlm.nih.gov/pubmed/30209169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00974-18
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