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Structure of Serotype 1 Reovirus Attachment Protein σ1 in Complex with Junctional Adhesion Molecule A Reveals a Conserved Serotype-Independent Binding Epitope

Mammalian orthoreoviruses use glycans and junctional adhesion molecule A (JAM-A) as attachment receptors. We determined the structure of serotype 1 reovirus attachment protein σ1 alone and in complex with JAM-A. Comparison with the structure of serotype 3 reovirus σ1 bound to JAM-A reveals that both...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Stettner, Eva, Dietrich, Melanie H., Reiss, Kerstin, Dermody, Terence S., Stehle, Thilo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442426/
https://ncbi.nlm.nih.gov/pubmed/25810543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00433-15
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