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A chimeric adenovirus vector encoding reovirus attachment protein σ1 targets cells expressing junctional adhesion molecule 1
The utility of adenovirus (Ad) vectors for gene transduction can be limited by receptor specificity. We developed a gene-delivery vehicle in which the potent Ad5 vector was genetically reengineered to display the mucosal-targeting σ1 protein of reovirus type 3 Dearing (T3D). A σ1 construct containin...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC395944/ https://ncbi.nlm.nih.gov/pubmed/15079060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400542101 |
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