Reovirus Neurotropism and Virulence Are Dictated by Sequences in the Head Domain of the Viral Attachment Protein

Viral capsid components that bind cellular receptors mediate critical functions in viral tropism and disease pathogenesis. Mammalian orthoreoviruses (reoviruses) spread systemically in newborn mice to cause serotype-specific disease in the central nervous system (CNS). Serotype 1 (T1) reovirus infec...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Sutherland, Danica M., Aravamudhan, Pavithra, Dietrich, Melanie H., Stehle, Thilo, Dermody, Terence S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2018
Gaiak:
Pathogenesis and Immunity
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232475/
https://ncbi.nlm.nih.gov/pubmed/30209169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00974-18
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