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A Single Point Mutation in the Rhinovirus 2B Protein Reduces the Requirement for Phosphatidylinositol 4-Kinase Class III Beta in Viral Replication

Rhinoviruses (RVs) replicate on cytoplasmic membranes derived from the Golgi apparatus. They encode membrane-targeted proteins 2B, 2C, and 3A, which control trafficking and lipid composition of the replication membrane. The virus recruits host factors for replication, such as phosphatidylinositol 4...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Roulin, Pascal S., Murer, Luca P., Greber, Urs F.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232462/
https://ncbi.nlm.nih.gov/pubmed/30209171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01462-18
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