Hepatitis B Spliced Protein (HBSP) Suppresses Fas-Mediated Hepatocyte Apoptosis via Activation of PI3K/Akt Signaling

Hepatitis B spliced protein (HBSP) is known to associate with viral persistence and pathogenesis; however, its biological and clinical significance remains poorly defined. Acquired resistance to Fas-mediated apoptosis is thought to be one of the major promotors for hepatitis B virus (HBV) chronicity...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Wu, Shu-Xiang, Chen, Wan-Nan, Jing, Zhen-Tang, Liu, Wei, Lin, Xin-Jian, Lin, Xu
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232459/
https://ncbi.nlm.nih.gov/pubmed/30209179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01273-18
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