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Dexmedetomidine activates the PI3K/Akt pathway to inhibit hepatocyte apoptosis in rats with obstructive jaundice

Obstructive jaundice (OJ) is a common disease in clinical surgery. The present study aimed to determine the effects of dexmedetomidine (Dex) on hepatocyte apoptosis in rats with OJ and also to explore the underlying mechanism. A total of 30 adult male Sprague Dawley rats were randomly divided into 3...

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Publicado en:Exp Ther Med
Autores principales: Xie, Yaying, Guo, Chunyan, Liu, Ye, Shi, Luanyuan, Yu, Jianshe
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6862008/
https://ncbi.nlm.nih.gov/pubmed/31772637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.8085
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