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Emodin-induced autophagy against cell apoptosis through the PI3K/AKT/mTOR pathway in human hepatocytes

BACKGROUND: Emodin, a major component of Polygonum multiflorum (PM), has been reported to exert both protective and toxic effects in several cell types. However, the effects and underlying mechanisms of action of emodin in hepatic cells are still obscure. METHODS: The present study used the normal h...

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Dades bibliogràfiques
Publicat a:Drug Des Devel Ther
Autors principals: Zheng, Xiao-yuan, Yang, Shi-ming, Zhang, Rong, Wang, Su-min, Li, Guo-bing, Zhou, Shi-wen
Format: Artigo
Idioma:Inglês
Publicat: Dove 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734549/
https://ncbi.nlm.nih.gov/pubmed/31564833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S204958
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