Induction of apoptosis and autophagy via mitochondria- and PI3K/Akt/mTOR-mediated pathways by E. adenophorum in hepatocytes of saanen goat

E. adenophorum has reported to cause hepatotoxicity. But, the precise effects of E. adenophorum on hepatocytes is unclear. Saanen goats were fed on E. adenophorum to detect the cytotoxicity effects of E. adenophorum on hepatocytes. Our study has shown that the typical apoptotic features, the increas...

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Bibliographic Details
Published in:Oncotarget
Main Authors: He, Yajun, Mo, Quan, Luo, Biao, Qiao, Yan, Xu, Ruiguang, Zuo, Zhicai, Deng, Junliang, Nong, Xiang, Peng, Guangneng, He, Wei, Wei, Yahui, Hu, Yanchun
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342361/
https://ncbi.nlm.nih.gov/pubmed/27391155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10402
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