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Euptox A Induces G1 Arrest and Autophagy via p38 MAPK- and PI3K/Akt/mTOR-Mediated Pathways in Mouse Splenocytes

Euptox A (9-oxo-10, 11-dehydroageraphorone), the main toxin isolated from Eupatorium adenophorum, is known to induce immunotoxicity in animals. However, the precise mechanism underlying the effects of Euptox A on splenocytes is unclear. Here, we aimed to investigate the molecular mechanisms underlyi...

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Detalhes bibliográficos
Publicado no:J Histochem Cytochem
Main Authors: Mo, Quan, Hu, Liwen, Weng, Jiahua, Zhang, Yong, Zhou, Yancheng, Xu, Ruiguang, Zuo, Zhicai, Deng, Junliang, Ren, Zhihua, Zhong, Zhijun, Peng, Guangneng, Nong, Xiang, Wei, Yahui, Hu, Yanchun
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582668/
https://ncbi.nlm.nih.gov/pubmed/28745544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/0022155417722118
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