Hepatitis B Virus Surface Antigen Enhances the Sensitivity of Hepatocytes to Fas-Mediated Apoptosis via Suppression of AKT Phosphorylation

The Fas receptor/ligand system plays a prominent role in hepatic apoptosis and hepatocyte death. Although hepatitis B virus (HBV) surface Ag (HBsAg) is the most abundant HBV protein in the liver and peripheral blood of patients with chronic HBV infection, its role in Fas-mediated hepatocyte apoptosi...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Jing, Zhen-Tang, Liu, Wei, Wu, Shu-Xiang, He, Yun, Lin, Yan-Ting, Chen, Wan-Nan, Lin, Xin-Jian, Lin, Xu
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2018
Assuntos:
Infectious Disease and Host Response
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176106/
https://ncbi.nlm.nih.gov/pubmed/30171166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800732
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