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Therapeutic Use of mTOR Inhibitors in Renal Diseases: Advances, Drawbacks, and Challenges

The mammalian (or mechanistic) target of rapamycin (mTOR) pathway has a key role in the regulation of a variety of biological processes pivotal for cellular life, aging, and death. Impaired activity of mTOR complexes (mTORC1/mTORC2), particularly mTORC1 overactivation, has been implicated in a pleth...

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Bibliografische gegevens
Gepubliceerd in:Oxid Med Cell Longev
Hoofdauteurs: Viana, Sofia D., Reis, Flávio, Alves, Rui
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231362/
https://ncbi.nlm.nih.gov/pubmed/30510618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3693625
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