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Recent Advances and Challenges of mTOR Inhibitors Use in the Treatment of Patients with Tuberous Sclerosis Complex

Tuberous sclerosis complex (TSC) is a genetic condition characterized by the presence of benign, noninvasive, and tumor-like lesions called hamartomas that can affect multiple organ systems and are responsible for the clinical features of the disease. In the majority of cases, TSC results from mutat...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Palavra, Filipe, Robalo, Conceição, Reis, Flávio
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5366202/
https://ncbi.nlm.nih.gov/pubmed/28386314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9820181
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