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Resveratrol Decreases Oxidative Stress by Restoring Mitophagy and Improves the Pathophysiology of Dystrophin-Deficient mdx Mice

We previously showed that treatment with resveratrol (3,5,4′-trihydroxy-trans-stilbene), an activator of the NAD(+)-dependent deacetylase SIRT1 at 4 g/kg food for 32 weeks, significantly decreased the muscular reactive oxygen species (ROS) levels and ameliorated the pathology of mdx mice, an animal...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oxid Med Cell Longev
Prif Awduron: Sebori, Rio, Kuno, Atsushi, Hosoda, Ryusuke, Hayashi, Takashi, Horio, Yoshiyuki
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Hindawi 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231358/
https://ncbi.nlm.nih.gov/pubmed/30510631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/9179270
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