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SIRT1 deficiency interferes with membrane resealing after cell membrane injury
Activation of SIRT1, an NAD(+)-dependent protein deacetylase, ameliorates muscular pathophysiology of δ-sarcoglycan-deficient TO-2 hamsters and dystrophin-deficient mdx mice. We found that SIRT1 was highly expressed beneath the cellular membranes of muscle cells. To elucidate functional roles of SIR...
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| 出版年: | PLoS One |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6594621/ https://ncbi.nlm.nih.gov/pubmed/31242212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218329 |
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