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Resveratrol Ameliorates Mitophagy Disturbance and Improves Cardiac Pathophysiology of Dystrophin-deficient mdx Mice

Autophagy activation improves the phenotype in mdx mice, a Duchenne muscular dystrophy (DMD) model, although the underlying mechanisms are obscure. We previously found that resveratrol, a strong inducer of autophagy, ameliorates the cardiac pathology of mdx mice. Autophagy could eliminate damaged mi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kuno, Atsushi, Hosoda, Ryusuke, Sebori, Rio, Hayashi, Takashi, Sakuragi, Hiromi, Tanabe, Mika, Horio, Yoshiyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197260/
https://ncbi.nlm.nih.gov/pubmed/30348945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33930-w
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