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Redox regulation of type-I inositol trisphosphate receptors in intact mammalian cells

A sensitization of inositol 1,4,5-trisphosphate receptor (IP(3)R)–mediated Ca(2+) release is associated with oxidative stress in multiple cell types. These effects are thought to be mediated by alterations in the redox state of critical thiols in the IP(3)R, but this has not been directly demonstrat...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Joseph, Suresh K., Young, Michael P., Alzayady, Kamil, Yule, David I., Ali, Mehboob, Booth, David M., Hajnóczky, György
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231128/
https://ncbi.nlm.nih.gov/pubmed/30228182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005624
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