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Redox regulation of type-I inositol trisphosphate receptors in intact mammalian cells

A sensitization of inositol 1,4,5-trisphosphate receptor (IP(3)R)–mediated Ca(2+) release is associated with oxidative stress in multiple cell types. These effects are thought to be mediated by alterations in the redox state of critical thiols in the IP(3)R, but this has not been directly demonstrat...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Joseph, Suresh K., Young, Michael P., Alzayady, Kamil, Yule, David I., Ali, Mehboob, Booth, David M., Hajnóczky, György
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231128/
https://ncbi.nlm.nih.gov/pubmed/30228182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005624
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