Age-dependent cardiac function during experimental sepsis: effect of pharmacological activation of AMP-activated protein kinase by AICAR

Age represents a major risk factor for multiple organ failure, including cardiac dysfunction, in patients with sepsis. AMP-activated protein kinase (AMPK) is a crucial regulator of energy homeostasis that controls mitochondrial biogenesis by activation of peroxisome proliferator-activated receptor-γ...

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Enregistré dans:
Détails bibliographiques
Publié dans:Am J Physiol Heart Circ Physiol
Auteurs principaux: Inata, Yu, Piraino, Giovanna, Hake, Paul W., O’Connor, Michael, Lahni, Patrick, Wolfe, Vivian, Schulte, Christine, Moore, Victoria, James, Jeanne M., Zingarelli, Basilia
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230907/
https://ncbi.nlm.nih.gov/pubmed/29979626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00052.2018
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