Support of bone mineral deposition by regulation of pH

Osteoblasts secrete collagen and isolate bone matrix from extracellular space. In the matrix, alkaline phosphatase generates phosphate that combines with calcium to form mineral, liberating 8 H(+) per 10 Ca(+2) deposited. However, pH-dependent hydroxyapatite deposition on bone collagen had not been...

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Gepubliceerd in:Am J Physiol Cell Physiol
Hoofdauteurs: Blair, Harry C., Larrouture, Quitterie C., Tourkova, Irina L., Liu, Li, Bian, Jing Hao, Stolz, Donna Beer, Nelson, Deborah J., Schlesinger, Paul H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230682/
https://ncbi.nlm.nih.gov/pubmed/30044661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00056.2018
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