Support of bone mineral deposition by regulation of pH

Osteoblasts secrete collagen and isolate bone matrix from extracellular space. In the matrix, alkaline phosphatase generates phosphate that combines with calcium to form mineral, liberating 8 H(+) per 10 Ca(+2) deposited. However, pH-dependent hydroxyapatite deposition on bone collagen had not been...

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Pubblicato in:Am J Physiol Cell Physiol
Autori principali: Blair, Harry C., Larrouture, Quitterie C., Tourkova, Irina L., Liu, Li, Bian, Jing Hao, Stolz, Donna Beer, Nelson, Deborah J., Schlesinger, Paul H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230682/
https://ncbi.nlm.nih.gov/pubmed/30044661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00056.2018
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