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Adrenocorticotropic hormone and 1,25-dihydroxyvitamin D3 enhance human osteogenesis in vitro by synergistically accelerating the expression of bone-specific genes

To improve definition of the physical and hormonal support of bone formation, we studied differentiation of human osteoblasts in vitro at varying combinations of ACTH, 1α,25-dihydroxyvitamin D(3) (1,25(OH)(2)D), and extracellular calcium, with and without added cortisol. Bone mineralization, alkalin...

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Dades bibliogràfiques
Publicat a:Lab Invest
Autors principals: Tourkova, Irina L, Liu, Li, Sutjarit, Nareerat, Larrouture, Quitterie C, Luo, Jianhua, Robinson, Lisa J, Blair, Harry C
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844701/
https://ncbi.nlm.nih.gov/pubmed/28737765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2017.62
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