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Sphingosine‐1‐Phosphate Modulates the Effect of Estrogen in Human Osteoblasts

Production of sphingosine‐1‐phosphate (S1P) is linked to 17β‐estradiol (E2) activity in many estrogen‐responsive cells; in bone development, the role of S1P is unclear. We studied effects of S1P on proliferation and differentiation of human osteoblasts (hOB). Ten nM E2, 1 μM S1P, or 1 μM of the S1P...

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Publicado en:JBMR Plus
Autores principales: Tantikanlayaporn, Duangrat, Tourkova, Irina L, Larrouture, Quitterie, Luo, Jianhua, Piyachaturawat, Pawinee, Witt, Michelle R, Blair, Harry C, Robinson, Lisa J
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095197/
https://ncbi.nlm.nih.gov/pubmed/30123862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm4.10037
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