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Adrenocorticotropic hormone and 1,25-dihydroxyvitamin D3 enhance human osteogenesis in vitro by synergistically accelerating the expression of bone-specific genes
To improve definition of the physical and hormonal support of bone formation, we studied differentiation of human osteoblasts in vitro at varying combinations of ACTH, 1α,25-dihydroxyvitamin D(3) (1,25(OH)(2)D), and extracellular calcium, with and without added cortisol. Bone mineralization, alkalin...
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| Pubblicato in: | Lab Invest |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5844701/ https://ncbi.nlm.nih.gov/pubmed/28737765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2017.62 |
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