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EFFECT OF LONG-TERM POLYPHARMACY AND THE DRUG BURDEN INDEX (DBI) ON CARDIAC FUNCTION AND FIBROSIS IN AGED MICE
Polypharmacy (use of ≥ 5 medications) and Drug Burden Index (DBI: measures cumulative exposure to anticholinergic and sedative drugs) impair function in older adults. Preclinical studies can provide a mechanistic understanding. We aim to evaluate the effect of chronic polypharmacy, medications with...
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| Publicado no: | Innov Aging |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6230101/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy023.371 |
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